Peter Angelo Simon has explored many forms of photographic expression in his wide-ranging career. His work has been featured in books, advertising campaigns, corporate communication, and magazines worldwide, including the New York Times Magazine and Smithsonian. His photographs have been exhibited in museums and galleries internationally. Simon has a deep interest in capturing the working processes of creative people. This comes across powerfully in his studies of theater director Robert Wilson, painter George Deem, the founders of New York's Big Apple Circus and, of course, Muhammad Ali. Simon co-produced the D. A. Pennebaker and Chris Hegedus documentary film, Bessie: A Portrait of Bessie Schonberg. Simon pioneered innovative photo illustration. His images often convey the feeling of embarking on a story or inner journey.

Peter Angelo Simon's work has been widely recognised, formally with him receiving Clio and the Andy awards (advertising), and by The Art Director's Club of New York, Art Direction Magazine, Communication Arts, and the Eastman Kodak Epcot Center Professional Photographer's Awards.

Books include GOAT (Taschen, 2004), Big Apple Circus (Penguin, 1978), and Muhammad Ali, Fighter’s Heaven 1974 (Reel Art Press, 2015).